Anti-Phospholipase A2 Receptor Antibodies in Membranous Nephropathy: from Bench to the Patient
نویسندگان
چکیده
Membranous nephropathy (MN) is a glomerular disease histologically characterized by an uniform thickening of glomerular basement membranes (GBM) caused by subepithelial electrondense deposits of immune complexes, in which the antibody is an IgG. In about 2/3 of cases the etiology of MN is unknown and the disease is called primary or idiopathic. In the remaining cases MN may be secondary to systemic or autoimmune diseases, malignancy, infections, toxic agents or drugs.
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